Japanese researchers have found that the skin aging by reprogramming skin cells into an embryonic stem cell-like state are reversed. It may sound complicated, but the only key to this process is the treatment of glycine, the scientists have found that the degeneration of the skin is inverted able.
Skin aging can be reversed
A team of scientists led by Professor Jun-Ichi Hayashi of the University of Tsukuba in Japan led disproved the theory that skin damage due to aging are my mitochondrial DNA mutations in the skin caused. They found that skin aging is made known epigenetic regulation available rather by another form of regulation of genes.
"Epigenetic Regulation refers to modifications such as the addition of chemical structures or
Proteins that modify the physical structure of DNA, which genes on or off, "the researchers wrote in their report. In contrast to mutations, epigenetic changes do not alter the DNA sequence of the skin itself.
Scientists have genes that reversed found skin aging
In their study, the researchers obtained samples of cells from the skin of young and elderly. Then reprogrammed human fibroblast cell lines from the skin to a similar state of embryonic stem cells are derived. The result showed that the reversal of the sample of skin cells in their elemental state, all skin damage was clear whether the sample from the young or elderly obtained.
After the discovery of these investment properties of the skin, the scientists saw then could control the epigenetic regulation of the skin. Then they found that genes is capable of producing skin glycine can also regulate epigenetic regulation. Thus, two genes were glycine were identified properties.
For 10 days, the researchers of the culture of the cell sample skin treatment 97 years old, with glycine. The end result was the skin sample, the aging process has completely reversed to convince.
Read the full scientific report: epigenetic regulation of nuclear encoded genes SHMT2 GCAT and are defects in human mitochondrial respiratory Age connected
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